Phase 3 repolarization in pacemaker cells is due to

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Multiple Choice

Phase 3 repolarization in pacemaker cells is due to

Explanation:
Phase 3 repolarization in pacemaker cells is driven by outward potassium currents while inward calcium currents diminish. As repolarization begins, voltage-gated K+ channels open and K+ leaves the cell, pulling the membrane potential back toward the resting level. At the same time, L-type calcium channels close/inactivate, reducing Ca2+ entry that would oppose repolarization. In pacemaker cells, the upstroke is actually produced by calcium influx, not sodium, so the key to phase 3 is the shift to strong K+ efflux with reduced Ca2+ influx. Chloride influx is not a major factor here.

Phase 3 repolarization in pacemaker cells is driven by outward potassium currents while inward calcium currents diminish. As repolarization begins, voltage-gated K+ channels open and K+ leaves the cell, pulling the membrane potential back toward the resting level. At the same time, L-type calcium channels close/inactivate, reducing Ca2+ entry that would oppose repolarization. In pacemaker cells, the upstroke is actually produced by calcium influx, not sodium, so the key to phase 3 is the shift to strong K+ efflux with reduced Ca2+ influx. Chloride influx is not a major factor here.

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